Carmustine-d8

• CAT Number: I044511
• Molecular Formula: C5HD8Cl2N3O2
• Molecular Weight: 222.10
• Purity: ≥95%
• Synonyms: 1,3-bis(2-chloro-1,1,2,2-tetradeuterioethyl)-1-nitrosourea
• InChI: InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)/i1D2,2D2,3D2,4D2
• InChIKey: DLGOEMSEDOSKAD-SVYQBANQSA-N
• SMILES: [2H]C([2H])(C([2H])([2H])Cl)NC(=O)N(C([2H])([2H])C([2H])([2H])Cl)N=O

Carmustine-d8（Cat No.:I044511）is a deuterated form of carmustine (BCNU), an alkylating agent used in chemotherapy for treating brain tumors, Hodgkin’s lymphoma, and multiple myeloma. In Carmustine-d8, eight hydrogen atoms are replaced with deuterium, providing enhanced stability and allowing its use as an internal standard in mass spectrometry and pharmacokinetic studies. Like the parent compound, it exerts cytotoxic effects by forming DNA cross-links that inhibit replication and transcription. Carmustine-d8 is essential for accurate quantification and metabolic profiling of carmustine in biological samples during drug development, therapeutic monitoring, and residue analysis.