For research use only. Not for therapeutic Use.
Carboxylesterase-IN-2（Cat No.:I044084）is a selective inhibitor of carboxylesterases (CES), enzymes that play a central role in the metabolism of esterified drugs, prodrugs, and xenobiotics. By inhibiting CES activity, this compound helps modulate drug activation, detoxification pathways, and lipid metabolism, particularly in liver and intestinal tissues where CES1 and CES2 are highly expressed. Carboxylesterase-IN-2 is widely used in ADME-Tox studies to evaluate enzyme-specific drug interactions and to enhance the stability and efficacy of ester-containing therapeutics. It is a valuable research tool for optimizing pharmacokinetic properties and studying metabolic resistance mechanisms.
| CAS Number | 2764748-88-9 |
| Synonyms | 6-(3,4-dimethylphenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one |
| Molecular Formula | C13H12N4OS |
| Purity | ≥95% |
| IUPAC Name | 6-(3,4-dimethylphenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one |
| InChI | InChI=1S/C13H12N4OS/c1-8-3-4-10(7-9(8)2)19-12-6-5-11-14-15-13(18)17(11)16-12/h3-7H,1-2H3,(H,15,18) |
| InChIKey | ZODAMEZBCMGEGI-UHFFFAOYSA-N |
| SMILES | CC1=C(C=C(C=C1)SC2=NN3C(=NNC3=O)C=C2)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
