Carbonic anhydrase inhibitor 2

• CAT Number: I044080
• CAS Number: 2758231-43-3
• Molecular Formula: C12H16N4O6S
• Molecular Weight: 344.34
• Purity: ≥95%
• Synonyms: methyl 2-[[2-[(4-sulfamoylphenyl)carbamoylamino]acetyl]amino]acetate
• InChI: InChI=1S/C12H16N4O6S/c1-22-11(18)7-14-10(17)6-15-12(19)16-8-2-4-9(5-3-8)23(13,20)21/h2-5H,6-7H2,1H3,(H,14,17)(H2,13,20,21)(H2,15,16,19)
• InChIKey: HYGAYYSZXIJQMB-UHFFFAOYSA-N
• SMILES: COC(=O)CNC(=O)CNC(=O)NC1=CC=C(C=C1)S(=O)(=O)N

Carbonic anhydrase inhibitor 2（Cat No.:I044080）is a selective small-molecule inhibitor targeting carbonic anhydrases (CAs), a family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. By blocking CA activity, this inhibitor disrupts pH regulation, CO₂ transport, and ion balance, making it valuable in studying glaucoma, epilepsy, cancer, and metabolic disorders. Carbonic anhydrase inhibitor 2 is especially useful in targeting tumor-associated isoforms like CA IX and CA XII, which contribute to acidic tumor microenvironments. It is widely used in oncology and physiology research for developing CA-targeted therapeutic strategies.