Candesartan

• CAT Number: A000781
• CAS Number: 139481-59-7
• Molecular Formula: C24H20N6O3
• Molecular Weight: 440.45
• Purity: ≥95%
• Synonyms: 139481-59-7; Blopress; Ratacand; 1-((2/’-(1H-Tetrazol-5-yl)-[1,1/’-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid; CV-11974
• Target: Vitamin D Related/Nuclear Receptor
• Solubility: >14.7mg/mL in DMSO
• Storage: -20°C
• IUPAC Name: 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid
• InChI: InChI=1S/C24H20N6O3/c1-2-33-24-25-20-9-5-8-19(23(31)32)21(20)30(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29)
• InChIKey: HTQMVQVXFRQIKW-UHFFFAOYSA-N
• SMILES: CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)O

Candesartan（Cat No.:A000781）is an angiotensin II receptor blocker (ARB) with the molecular formula C24H20N6O3, used to treat hypertension and heart failure. It works by selectively blocking the angiotensin II type 1 (AT1) receptor, preventing vasoconstriction and aldosterone secretion, thereby lowering blood pressure and reducing cardiac workload. Administered orally, candesartan is typically used once daily and may be combined with other antihypertensives. It improves cardiovascular outcomes, particularly in patients with left ventricular dysfunction. Candesartan is generally well-tolerated, with side effects like dizziness or fatigue being mild and uncommon. It requires regular blood pressure monitoring.