Calcium phosphate, dibasic

• CAT Number: I023974
• CAS Number: 7757-93-9
• Molecular Formula: CaHO4P
• Molecular Weight: 136.06
• Purity: 98%
• Solubility: Soluble in DMSO
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: calcium hydrogen phosphate
• InChI: InChI=1S/Ca.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+2;/p-2
• InChIKey: FUFJGUQYACFECW-UHFFFAOYSA-L
• SMILES: P(O)(=O)([O-])[O-].[Ca+2]

Calcium hydrogen phosphate (Cat. No.: I023974) is a compound that can be used as a buffer, relaxant, yeast feed, emulsifier, curing agent, antioxidant synergist, and stabilizer. It can also be used as a base fertilizer for various crops.

Reference

1: Li M, Zhang J, Wang L, Wang B, Putnis CV. Mechanisms of Modulation of Calcium Phosphate Pathological Mineralization by Mobile and Immobile Small-Molecule Inhibitors. J Phys Chem B. 2018 Feb 8;122(5):1580-1587. doi: 10.1021/acs.jpcb.7b10956. Epub 2018 Jan 27. PubMed PMID: 29346735.
2: Zhang F, Adeola O. True is more additive than apparent total tract digestibility of calcium in limestone and dicalcium phosphate for twenty-kilogram pigs fed semipurified diets. J Anim Sci. 2017 Dec;95(12):5466-5473. doi: 10.2527/jas2017.1849. PubMed PMID: 29293744.
3: Grote S, Kleinebudde P. Roll Compaction/Dry Granulation of Dibasic Calcium Phosphate Anhydrous-Does the Morphology of the Raw Material Influence the Tabletability of Dry Granules? J Pharm Sci. 2018 Apr;107(4):1104-1111. doi: 10.1016/j.xphs.2017.12.003. Epub 2017 Dec 14. PubMed PMID: 29247739.
4: Kunisch E, Maenz S, Knoblich M, Ploeger F, Jandt KD, Bossert J, Kinne RW, Alsalameh S. Short-time pre-washing of brushite-forming calcium phosphate cement improves its in vitro cytocompatibility. Tissue Cell. 2017 Dec;49(6):697-710. doi: 10.1016/j.tice.2017.10.002. Epub 2017 Oct 14. PubMed PMID: 29102397.
5: Gandolfi MG, Zamparini F, Degli Esposti M, Chiellini F, Aparicio C, Fava F, Fabbri P, Taddei P, Prati C. Polylactic acid-based porous scaffolds doped with calcium silicate and dicalcium phosphate dihydrate designed for biomedical application. Mater Sci Eng C Mater Biol Appl. 2018 Jan 1;82:163-181. doi: 10.1016/j.msec.2017.08.040. Epub 2017 Aug 12. PubMed PMID: 29025644.
6: Dabiri SMH, Lagazzo A, Barberis F, Shayganpour A, Finocchio E, Pastorino L. New in-situ synthetized hydrogel composite based on alginate and brushite as a potential pH sensitive drug delivery system. Carbohydr Polym. 2017 Dec 1;177:324-333. doi: 10.1016/j.carbpol.2017.08.046. Epub 2017 Aug 14. PubMed PMID: 28962775.
7: Nykamp SG. Dual-energy computed tomography of canine uroliths. Am J Vet Res. 2017 Oct;78(10):1150-1155. doi: 10.2460/ajvr.78.10.1150. PubMed PMID: 28945133.
8: Xu X, Hu X, Ding Z, Chen Y. Effects of copyrolysis of sludge with calcium carbonate and calcium hydrogen phosphate on chemical stability of carbon and release of toxic elements in the resultant biochars. Chemosphere. 2017 Dec;189:76-85. doi: 10.1016/j.chemosphere.2017.09.021. Epub 2017 Sep 8. PubMed PMID: 28930666.
9: Murray KA, Collins MN, O’Sullivan RP, Ren G, Devine DM, Murphy A, Sadło J, O’Sullivan C, McEvoy B, Vrain O, O’Neill C, Insley G. Influence of gamma and electron beam sterilization on the stability of a premixed injectable calcium phosphate cement for trauma indications. J Mech Behav Biomed Mater. 2018 Jan;77:116-124. doi: 10.1016/j.jmbbm.2017.09.002. Epub 2017 Sep 5. PubMed PMID: 28898722.
10: Panahi F, Rabiee SM, Shidpour R. Synergic effect of chitosan and dicalcium phosphate on tricalcium silicate-based nanocomposite for root-end dental application. Mater Sci Eng C Mater Biol Appl. 2017 Nov 1;80:631-641. doi: 10.1016/j.msec.2017.07.012. Epub 2017 Jul 12. PubMed PMID: 28866210.
11: Paul S, Sun CC. The suitability of common compressibility equations for characterizing plasticity of diverse powders. Int J Pharm. 2017 Oct 30;532(1):124-130. doi: 10.1016/j.ijpharm.2017.08.096. Epub 2017 Aug 24. PubMed PMID: 28844895.
12: Reynolds GK, Campbell JI, Roberts RJ. A compressibility based model for predicting the tensile strength of directly compressed pharmaceutical powder mixtures. Int J Pharm. 2017 Oct 5;531(1):215-224. doi: 10.1016/j.ijpharm.2017.08.075. Epub 2017 Aug 18. PubMed PMID: 28823886.
13: Kawakami M, Kitada R, Kurita T, Tokumura T. A Method for Decreasing the Amount of the Drug Remaining on the Surfaces of the Mortar and Pestle after Grinding Small Amount of Tablets. Yakugaku Zasshi. 2017;137(8):1017-1025. doi: 10.1248/yakushi.17-00041. Japanese. PubMed PMID: 28768941.
14: Oryan A, Alidadi S, Bigham-Sadegh A. Dicalcium Phosphate Anhydrous: An Appropriate Bioceramic in Regeneration of Critical-Sized Radial Bone Defects in Rats. Calcif Tissue Int. 2017 Nov;101(5):530-544. doi: 10.1007/s00223-017-0309-9. Epub 2017 Jul 31. PubMed PMID: 28761974.
15: Ajaxon I, Acciaioli A, Lionello G, Ginebra MP, Öhman-Mägi C, Baleani M, Persson C. Elastic properties and strain-to-crack-initiation of calcium phosphate bone cements: Revelations of a high-resolution measurement technique. J Mech Behav Biomed Mater. 2017 Oct;74:428-437. doi: 10.1016/j.jmbbm.2017.06.023. Epub 2017 Jun 21. PubMed PMID: 28735216.
16: Sugiura Y, Tsuru K, Ishikawa K. “Fabrication of arbitrarily shaped carbonate apatite foam based on the interlocking process of dicalcium hydrogen phosphate dihydrate”. J Mater Sci Mater Med. 2017 Aug;28(8):122. doi: 10.1007/s10856-017-5937-0. Epub 2017 Jul 8. PubMed PMID: 28689353.
17: Gallob J, Sufi F, Amini P, Siddiqi M, Mason S. A randomised exploratory clinical evaluation of dentifrices used as controls in dentinal hypersensitivity studies. J Dent. 2017 Sep;64:80-87. doi: 10.1016/j.jdent.2017.06.009. Epub 2017 Jun 23. PubMed PMID: 28652142.
18: Bungartz M, Kunisch E, Maenz S, Horbert V, Xin L, Gunnella F, Mika J, Borowski J, Bischoff S, Schubert H, Sachse A, Illerhaus B, Günster J, Bossert J, Jandt KD, Plöger F, Kinne RW, Brinkmann O. GDF5 significantly augments the bone formation induced by an injectable, PLGA fiber-reinforced, brushite-forming cement in a sheep defect model of lumbar osteopenia. Spine J. 2017 Nov;17(11):1685-1698. doi: 10.1016/j.spinee.2017.06.007. Epub 2017 Jun 19. PubMed PMID: 28642196.
19: Gunnella F, Kunisch E, Bungartz M, Maenz S, Horbert V, Xin L, Mika J, Borowski J, Bischoff S, Schubert H, Hortschansky P, Sachse A, Illerhaus B, Günster J, Bossert J, Jandt KD, Plöger F, Kinne RW, Brinkmann O. Low-dose BMP-2 is sufficient to enhance the bone formation induced by an injectable, PLGA fiber-reinforced, brushite-forming cement in a sheep defect model of lumbar osteopenia. Spine J. 2017 Nov;17(11):1699-1711. doi: 10.1016/j.spinee.2017.06.005. Epub 2017 Jun 12. PubMed PMID: 28619686.
20: Cama G, Nkhwa S, Gharibi B, Lagazzo A, Cabella R, Carbone C, Dubruel P, Haugen H, Di Silvio L, Deb S. The role of new zinc incorporated monetite cements on osteogenic differentiation of human mesenchymal stem cells. Mater Sci Eng C Mater Biol Appl. 2017 Sep 1;78:485-494. doi: 10.1016/j.msec.2017.04.086. Epub 2017 Apr 20. PubMed PMID: 28576013.