CA77.1

For research use only. Not for therapeutic Use.

  • CAT Number: I044527
  • CAS Number: 2412270-22-3
  • Molecular Formula: C16H12ClN3O
  • Molecular Weight: 297.74
  • Purity: ≥95%
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CA77.1(Cat No.:I044527)is a small-molecule inhibitor targeting the carbohydrate sulfotransferase CHST15, an enzyme involved in the sulfation of chondroitin sulfate E (CS-E), a glycosaminoglycan associated with fibrosis and tumor progression. By inhibiting CHST15, CA77.1 reduces the production of CS-E, thereby modulating extracellular matrix remodeling, cell adhesion, and signaling pathways linked to inflammation and fibrotic disease. It has shown promise in preclinical models for treating conditions such as idiopathic pulmonary fibrosis and pancreatic cancer. CA77.1 is a valuable tool for studying glycosaminoglycan biosynthesis and developing novel anti-fibrotic and anti-tumor therapies.


CAS Number 2412270-22-3
Synonyms

N-[4-(6-chloroquinoxalin-2-yl)phenyl]acetamide

Molecular Formula C16H12ClN3O
Purity ≥95%
IUPAC Name N-[4-(6-chloroquinoxalin-2-yl)phenyl]acetamide
InChI InChI=1S/C16H12ClN3O/c1-10(21)19-13-5-2-11(3-6-13)16-9-18-15-8-12(17)4-7-14(15)20-16/h2-9H,1H3,(H,19,21)
InChIKey ZQXMPDVGBWOTBY-UHFFFAOYSA-N
SMILES CC(=O)NC1=CC=C(C=C1)C2=CN=C3C=C(C=CC3=N2)Cl
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