C20 Ceramide

• CAT Number: R001215
• CAS Number: 7344-02-7
• Molecular Formula: C38H75NO3
• Molecular Weight: 594.01
• Purity: ≥95%
• Synonyms: N-[(E,2S,3R)-1,3-dihydroxyoctadec-4-en-2-yl]icosanamide
• InChI: InChI=1S/C38H75NO3/c1-3-5-7-9-11-13-15-17-18-19-20-22-24-26-28-30-32-34-38(42)39-36(35-40)37(41)33-31-29-27-25-23-21-16-14-12-10-8-6-4-2/h31,33,36-37,40-41H,3-30,32,34-35H2,1-2H3,(H,39,42)/b33-31+/t36-,37+/m0/s1
• InChIKey: XWBWIAOWSABHFI-NUKVNZTCSA-N
• SMILES: CCCCCCCCCCCCCCCCCCCC(=O)NC(CO)C(C=CCCCCCCCCCCCCC)O

C20 Ceramide (Cat No.: R001215) is a naturally occurring sphingolipid composed of a sphingosine backbone linked to a 20-carbon fatty acid chain. As a bioactive lipid mediator, it plays a central role in regulating apoptosis, cell cycle arrest, differentiation, and stress responses. C20 ceramide is also involved in membrane structure and signaling, contributing to lipid raft formation and receptor clustering. In research, it is widely used to study sphingolipid metabolism, programmed cell death, and ceramide-mediated pathways in cancer, neurobiology, and metabolic diseases.

Reference

[1]. Cowart LA. Sphingolipids: players in the pathology of metabolic disease. Trends Endocrinol Metab. 2009 Jan;20(1):34-42.
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[2]. Pewzner-Jung, Y., Ben-Dor, S., and Futerman, A.H. When do lasses (longevity assurance genes) become CerS (ceramide synthases)? The Journal of Biological Chemisty 281(35), 25001-25005 (2006).
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