For research use only. Not for therapeutic Use.
Butyryltimolol（Cat No.:M013084）is a lipophilic ester derivative of timolol, a non-selective β-adrenergic receptor antagonist primarily used to reduce intraocular pressure in glaucoma. The butyryl ester modification enhances corneal permeability and prolongs ocular residence time, improving drug delivery and therapeutic efficacy. Upon ocular administration, butyryltimolol is hydrolyzed by esterases to release the active parent compound, timolol. This prodrug approach minimizes systemic absorption and associated side effects. Butyryltimolol is investigated in ophthalmic research for optimized beta-blocker formulations, offering improved bioavailability and sustained intraocular pressure control in glaucoma treatment.
| CAS Number | 106351-79-5 |
| Synonyms | [(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-yl] butanoate |
| Molecular Formula | C17H30N4O4S |
| Purity | ≥95% |
| IUPAC Name | [(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-yl] butanoate |
| InChI | InChI=1S/C17H30N4O4S/c1-5-6-14(22)25-13(11-18-17(2,3)4)12-24-16-15(19-26-20-16)21-7-9-23-10-8-21/h13,18H,5-12H2,1-4H3/t13-/m0/s1 |
| InChIKey | IGJCFKQCZRWRRM-ZDUSSCGKSA-N |
| SMILES | CCCC(=O)O[C@@H](CNC(C)(C)C)COC1=NSN=C1N2CCOCC2 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
