Burgess Reagent

• CAT Number: R030141
• CAS Number: 29684-56-8
• Molecular Formula: C₈H₁₈N₂O₄S
• Molecular Weight: 238.30
• Purity: ≥95%
• Synonyms: N,N-Diethyl-N-[[(methoxycarbonyl)amino]sulfonyl]-ethanaminium Inner Salt; (Carboxysulfamoyl)triethyl-ammonium Hydroxide Inner Salt Methyl Ester; 3,3,3-Triethyl-1-(methoxycarbonyl)diazathian-3-ium-1-ide 2,2-dioxide
• Storage: -20°C
• IUPAC Name: (1E)-1-methoxy-N-(triethylazaniumyl)sulfonylmethanimidate
• InChI: InChI=1S/C8H18N2O4S/c1-5-10(6-2,7-3)15(12,13)9-8(11)14-4/h5-7H2,1-4H3
• InChIKey: YSHOWEKUVWPFNR-UHFFFAOYSA-N
• SMILES: CC[N+](CC)(CC)S(=O)(=O)/N=C(\[O-])/OC

Burgess Reagent（Cat No.:R030141）, chemically known as methyl N-(triethylammoniumsulfonyl)carbamate, is a mild, selective dehydrating agent primarily used to convert secondary and tertiary alcohols into alkenes under non-acidic conditions. It appears as a white crystalline solid and is soluble in common organic solvents. Its unique advantage lies in its compatibility with base-sensitive compounds, making it valuable in complex organic synthesis. The reaction proceeds via syn-elimination, offering predictable stereoselectivity. Burgess Reagent is widely used in pharmaceuticals and natural product chemistry due to its efficiency, mildness, and clean reaction profiles.