For research use only. Not for therapeutic Use.
Buflomedil Hydrochloride (Cat No.: A000259) is a vasoactive drug primarily used to treat peripheral vascular diseases, such as intermittent claudication and chronic arterial occlusive disorders. It acts as an α-adrenergic receptor antagonist, improving blood flow by dilating peripheral blood vessels and enhancing microcirculation. Buflomedil also exhibits hemorheological effects by reducing blood viscosity and improving erythrocyte flexibility. Though once widely used in Europe, its clinical use has declined due to concerns over severe neurological and cardiac side effects, prompting regulatory restrictions in several countries.
| CAS Number | 35543-24-9 |
| Synonyms | NA |
| Molecular Formula | C17H25NO4.HCl |
| Purity | ≥95% |
| Storage | 3 years -20C powder |
| IUPAC Name | 4-pyrrolidin-1-yl-1-(2,4,6-trimethoxyphenyl)butan-1-one;hydrochloride |
| InChI | 1S/C17H25NO4.ClH/c1-20-13-11-15(21-2)17(16(12-13)22-3)14(19)7-6-10-18-8-4-5-9-18;/h11-12H,4-10H2,1-3H3;1H |
| InChIKey | ZDPACSAHMZADFZ-UHFFFAOYSA-N |
| SMILES | COC1=CC(=C(C(=C1)OC)C(=O)CCCN2CCCC2)OC.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
