For research use only. Not for therapeutic Use.
BSc5367（Cat No.:I044048）is a selective inhibitor of signal transducer and activator of transcription 3 (STAT3), a transcription factor involved in regulating genes critical for cell proliferation, survival, and immune evasion. By blocking STAT3 phosphorylation and dimerization, BSc5367 disrupts its nuclear translocation and transcriptional activity, suppressing oncogenic and inflammatory signaling. This compound is particularly valuable in cancer research, especially in tumors exhibiting constitutive STAT3 activation. BSc5367 also aids in studying immune modulation and cytokine signaling pathways, supporting therapeutic exploration of STAT3 inhibition in cancer, autoimmune diseases, and chronic inflammatory conditions.
| CAS Number | 3029584-84-4 |
| Synonyms | methyl 3-(3-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridin-5-yl)benzoate |
| Molecular Formula | C20H15N3O2 |
| Purity | ≥95% |
| IUPAC Name | methyl 3-(3-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridin-5-yl)benzoate |
| InChI | InChI=1S/C20H15N3O2/c1-25-20(24)14-5-2-4-13(8-14)16-9-17-18(12-23-19(17)22-11-16)15-6-3-7-21-10-15/h2-12H,1H3,(H,22,23) |
| InChIKey | GZHRICWZECSYJT-UHFFFAOYSA-N |
| SMILES | COC(=O)C1=CC=CC(=C1)C2=CC3=C(NC=C3C4=CN=CC=C4)N=C2 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
