Bromo-PEG8-Boc

• CAT Number: I016467
• CAS Number: 1623792-00-6
• Molecular Formula: C23H45BrO10
• Molecular Weight: 561.50
• Purity: ≥95%
• Synonyms: tert-butyl 3-[2-[2-[2-[2-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
• InChI: InChI=1S/C23H45BrO10/c1-23(2,3)34-22(25)4-6-26-8-10-28-12-14-30-16-18-32-20-21-33-19-17-31-15-13-29-11-9-27-7-5-24/h4-21H2,1-3H3
• InChIKey: DXYYTZDPNRZUDL-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCBr

Bromo-PEG8-Boc(CAT: I016467) is a versatile heterobifunctional linker featuring a terminal bromide group and a Boc-protected amine connected by a PEG8 spacer. The bromide enables nucleophilic substitution or thiol alkylation, while the Boc-protected amine can be deprotected under mild acidic conditions to yield a free primary amine for further coupling reactions. The PEG8 chain enhances hydrophilicity, solubility, and molecular flexibility, reducing steric hindrance in bioconjugation processes. This reagent is widely used in drug discovery, polymer modification, surface functionalization, and the synthesis of antibody–drug conjugates (ADCs). Bromo-PEG8-Boc provides a reliable tool for constructing multifunctional biomolecules and advanced materials.