For research use only. Not for therapeutic Use.
Bromo-PEG4-MS (Cat No.: I045416) is a heterobifunctional polyethylene glycol (PEG) linker containing four ethylene glycol units that provide hydrophilicity, flexibility, and reduced steric hindrance. It features a terminal bromide group for nucleophilic substitution and a methanesulfonate (mesylate, MS) group as an efficient leaving group for diverse coupling reactions. The PEG4 spacer enhances solubility in aqueous and organic media, facilitating versatile chemical modifications. This reagent is widely used in bioconjugation, surface functionalization, polymer modification, and the synthesis of multifunctional molecules for chemical biology and biomedical research applications.
| CAS Number | 2167807-41-0 |
| Synonyms | 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethyl methanesulfonate |
| Molecular Formula | C9H19BrO6S |
| Purity | ≥95% |
| InChI | InChI=1S/C9H19BrO6S/c1-17(11,12)16-9-8-15-7-6-14-5-4-13-3-2-10/h2-9H2,1H3 |
| InChIKey | LUIMQGOWWSFHND-UHFFFAOYSA-N |
| SMILES | CS(=O)(=O)OCCOCCOCCOCCBr |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
