Bromo-PEG2-phosphonic acid diethyl ester

• CAT Number: I016524
• CAS Number: 1226767-94-7
• Molecular Formula: C10H22BrO5P
• Molecular Weight: 333.16
• Purity: ≥95%
• Synonyms: 1-(2-bromoethoxy)-2-(2-diethoxyphosphorylethoxy)ethane
• InChI: InChI=1S/C10H22BrO5P/c1-3-15-17(12,16-4-2)10-9-14-8-7-13-6-5-11/h3-10H2,1-2H3
• InChIKey: BYTKSVRXAWIJCM-UHFFFAOYSA-N
• SMILES: CCOP(=O)(CCOCCOCCBr)OCC

Bromo-PEG2-phosphonic acid diethyl ester(CAT: I016524) is a reactive bifunctional polyethylene glycol derivative that combines a terminal bromo group with a phosphonic acid diethyl ester moiety, connected through a short PEG2 spacer. The bromo group acts as an electrophilic handle for nucleophilic substitution, enabling covalent attachment to amines, thiols, or other reactive species. The PEG2 segment enhances solubility and flexibility, while the phosphonic acid ester provides a protected functionality that can be hydrolyzed to yield a phosphonic acid for strong binding to metal oxide surfaces. This versatile linker is useful in surface modification, bioconjugation, and nanomaterial functionalization where controlled reactivity and stable immobilization are required.