For research use only. Not for therapeutic Use.
BRD2492 (CAT: I023663) is a potent and selective inhibitor of histone deacetylases HDAC1 and HDAC2, with IC₅₀ values of 13.2 nM and 77.2 nM, respectively. It demonstrates over 100-fold selectivity for HDAC1/2 over HDAC3 and HDAC6, making it an excellent tool for epigenetic research. BRD2492 effectively inhibits breast cancer cell proliferation, with IC₅₀ values of 1.01 μM in T-47D cells and 11.13 μM in MCF-7 cells. This compound is valuable for studying transcriptional regulation, chromatin remodeling, and anticancer drug development.
| CAS Number | 1821669-43-5 |
| Synonyms | 4-acetamido-N-(2-amino-5-pyridin-4-ylphenyl)benzamide |
| Molecular Formula | C20H18N4O2 |
| Purity | ≥95% |
| IUPAC Name | 4-acetamido-N-(2-amino-5-pyridin-4-ylphenyl)benzamide |
| InChI | InChI=1S/C20H18N4O2/c1-13(25)23-17-5-2-15(3-6-17)20(26)24-19-12-16(4-7-18(19)21)14-8-10-22-11-9-14/h2-12H,21H2,1H3,(H,23,25)(H,24,26) |
| InChIKey | BBHURYMVPMFILR-UHFFFAOYSA-N |
| SMILES | CC(=O)NC1=CC=C(C=C1)C(=O)NC2=C(C=CC(=C2)C3=CC=NC=C3)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
