Brain Natriuretic Peptide-45, mouse

• CAT Number: I044291
• CAS Number: 1816939-52-2
• Molecular Formula: C209H354N70O63S2
• Molecular Weight: 4919.61
• Purity: ≥95%
• IUPAC Name: (2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(4R,10S,13S,16S,19S,22S,28S,31S,34S,37S,40S,43S,49S,52R)-52-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-5-amino-2-[[(2S)-1-[(2S)-2-[[(2S)-5-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[2-[[(2S)-5-amino-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-5-oxopentanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-methylbutanoyl]amino]-5-oxopentanoyl]amino]-5-oxopentanoyl]amino]-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-4-oxobutanoyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-40-(4-aminobutyl)-49-benzyl-28,37-bis[(2S)-butan-2-yl]-13,31-bis(3-carbamimidamidopropyl)-34-(carboxymethyl)-16,22-bis(hydroxymethyl)-43-(1H-imidazol-4-ylmethyl)-10-(2-methylpropyl)-6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51-hexadecaoxo-19-propan-2-yl-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-hexadecazacyclotripentacontane-4-carbonyl]amino]-4-oxobutanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoic acid
• InChI: InChI=1S/C209H354N70O63S2/c1-26-105(20)160-196(332)237-85-154(297)242-137(87-281)191(327)273-158(103(16)17)198(334)268-141(91-285)188(324)251-118(48-38-64-230-206(220)221)171(307)257-126(69-97(4)5)168(304)235-84-155(298)244-143(193(329)261-133(77-150(218)293)179(315)240-108(23)165(301)256-127(70-98(6)7)180(316)246-115(45-32-35-61-210)170(306)258-128(71-99(8)9)182(318)265-136(205(341)342)73-101(12)13)93-343-344-94-144(194(330)259-130(74-111-43-30-29-31-44-111)169(305)236-82-152(295)241-131(75-112-80-228-95-238-112)183(319)247-117(47-34-37-63-212)177(313)275-161(106(21)27-2)200(336)264-135(79-156(299)300)185(321)249-120(178(314)274-160)50-40-66-232-208(224)225)270-190(326)140(90-284)267-189(325)142(92-286)269-201(337)162(107(22)28-3)276-186(322)132(76-113-81-229-96-239-113)263-203(339)164(110(25)288)278-199(335)159(104(18)19)272-175(311)116(46-33-36-62-211)250-187(323)139(89-283)266-184(320)134(78-151(219)294)260-174(310)123(55-59-148(216)291)253-195(331)145-52-42-68-279(145)204(340)125(51-41-67-233-209(226)227)255-173(309)122(54-58-147(215)290)252-172(308)124(56-60-149(217)292)254-197(333)157(102(14)15)271-176(312)119(49-39-65-231-207(222)223)248-181(317)129(72-100(10)11)262-202(338)163(109(24)287)277-192(328)138(88-282)243-153(296)83-234-167(303)121(53-57-146(214)289)245-166(302)114(213)86-280/h29-31,43-44,80-81,95-110,114-145,157-164,280-288H,26-28,32-42,45-79,82-94,210-213H2,1-25H3,(H2,214,289)(H2,215,290)(H2,216,291)(H2,217,292)(H2,218,293)(H2,219,294)(H,228,238)(H,229,239)(H,234,303)(H,235,304)(H,236,305)(H,237,332)(H,240,315)(H,241,295)(H,242,297)(H,243,296)(H,244,298)(H,245,302)(H,246,316)(H,247,319)(H,248,317)(H,249,321)(H,250,323)(H,251,324)(H,252,308)(H,253,331)(H,254,333)(H,255,309)(H,256,301)(H,257,307)(H,258,306)(H,259,330)(H,260,310)(H,261,329)(H,262,338)(H,263,339)(H,264,336)(H,265,318)(H,266,320)(H,267,325)(H,268,334)(H,269,337)(H,270,326)(H,271,312)(H,272,311)(H,273,327)(H,274,314)(H,275,313)(H,276,322)(H,277,328)(H,278,335)(H,299,300)(H,341,342)(H4,220,221,230)(H4,222,223,231)(H4,224,225,232)(H4,226,227,233)/t105-,106-,107-,108-,109+,110+,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,157-,158-,159-,160-,161-,162-,163-,164-/m0/s1
• InChIKey: HORSYDXFUMMCFJ-MMBYWGHXSA-N
• SMILES: CC[C@H](C)[C@H]1C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCCNC(=N)N)CC(=O)O)[C@@H](C)CC)CCCCN)CC2=CNC=N2)CC3=CC=CC=C3)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CC4=CNC=N4)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@@H]5CCCN5C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CO)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O)CC(C)C)CCCNC(=N)N)CO)C(C)C)CO

Brain Natriuretic Peptide-45 (BNP-45), mouse（Cat No.:I044291）is a 45-amino acid peptide hormone primarily produced in the heart’s ventricles. It plays a critical role in cardiovascular homeostasis by promoting vasodilation, natriuresis, and diuresis, ultimately reducing blood volume and pressure. BNP-45 exerts its effects by binding to natriuretic peptide receptors and stimulating cyclic GMP production. In mice, it serves as a key biomarker and therapeutic target in heart failure and hypertension research. BNP-45 is widely used in preclinical studies to investigate cardiac function, fluid regulation, and the molecular mechanisms underlying cardiovascular disease.