Bradykinin

  • CAT Number: P000190
  • CAS Number: 58-82-2
  • Molecular Formula: C50H73N15O11
  • Molecular Weight: 1060.22
  • Purity: ≥95%
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Bradykinin(Cat No.:P000190), is a physiologically active peptide involved in various biological processes. It plays a crucial role in vasodilation, inflammation, pain sensation, and regulation of blood pressure. Bradykinin is formed through enzymatic cleavage of kininogens and acts by binding to specific receptors. Its actions include increasing blood vessel permeability and promoting the release of other signaling molecules. While it contributes to normal physiological responses, excessive bradykinin production is associated with conditions like hereditary angioedema and contributes to symptoms like swelling and pain.

Catalog Number P000190
CAS Number 58-82-2
Molecular Formula

C50H73N15O11

Purity 95%
Solubility Soluble to 1 mg/ml in water
Storage −20°C
IUPAC Name (2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
InChI InChI=1S/C50H73N15O11/c51-32(16-7-21-56-49(52)53)45(72)65-25-11-20-39(65)47(74)64-24-9-18-37(64)43(70)58-28-40(67)59-34(26-30-12-3-1-4-13-30)41(68)62-36(29-66)46(73)63-23-10-19-38(63)44(71)61-35(27-31-14-5-2-6-15-31)42(69)60-33(48(75)76)17-8-22-57-50(54)55/h1-6,12-15,32-39,66H,7-11,16-29,51H2,(H,58,70)(H,59,67)(H,60,69)(H,61,71)(H,62,68)(H,75,76)(H4,52,53,56)(H4,54,55,57)/t32-,33-,34-,35-,36-,37-,38-,39-/m0/s1
InChIKey QXZGBUJJYSLZLT-FDISYFBBSA-N
SMILES C1CC(N(C1)C(=O)C2CCCN2C(=O)C(CCCN=C(N)N)N)C(=O)NCC(=O)NC(CC3=CC=CC=C3)C(=O)NC(CO)C(=O)N4CCCC4C(=O)NC(CC5=CC=CC=C5)C(=O)NC(CCCN=C(N)N)C(=O)O

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