For research use only. Not for therapeutic Use.
Br-DAPI (Cat No.:I044988) is a halogenated derivative of the classic DNA-binding dye DAPI, designed to enhance photophysical properties and enable photodynamic activity. Like DAPI, Br-DAPI binds strongly to A-T rich regions of double-stranded DNA, exhibiting bright blue fluorescence (excitation/emission ~358/461 nm). The bromination enhances intersystem crossing, making it useful in studies involving photosensitization and potential DNA photo-damage mechanisms. Br-DAPI is commonly used in fluorescence microscopy, live and fixed cell imaging, and DNA quantification. It is ideal for applications requiring nuclear staining with added photoreactivity.
| CAS Number | 2387906-44-5 |
| Synonyms | 3-bromo-2-(4-carbamimidoylphenyl)-1H-indole-6-carboximidamide |
| Molecular Formula | C16H14BrN5 |
| Purity | ≥95% |
| IUPAC Name | 3-bromo-2-(4-carbamimidoylphenyl)-1H-indole-6-carboximidamide |
| InChI | InChI=1S/C16H14BrN5/c17-13-11-6-5-10(16(20)21)7-12(11)22-14(13)8-1-3-9(4-2-8)15(18)19/h1-7,22H,(H3,18,19)(H3,20,21) |
| InChIKey | GSBXNZFEZFIMCS-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1C2=C(C3=C(N2)C=C(C=C3)C(=N)N)Br)C(=N)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
