Boc-NH-PEG2-CH2CH2COOH

• CAT Number: I014729
• CAS Number: 1365655-91-9
• Molecular Formula: C12H23NO6
• Molecular Weight: 277.31
• Purity: ≥95%
• Synonyms: 3-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]propanoic acid
• InChI: InChI=1S/C12H23NO6/c1-12(2,3)19-11(16)13-5-7-18-9-8-17-6-4-10(14)15/h4-9H2,1-3H3,(H,13,16)(H,14,15)
• InChIKey: OZMXZVCAXAQCHJ-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)NCCOCCOCCC(=O)O

Boc-NH-PEG2-CH2CH2COOH(CAT: I014729) is a bifunctional polyethylene glycol (PEG) derivative designed for versatile linker chemistry. It contains a Boc-protected amine group that can be selectively deprotected under acidic conditions, and a terminal carboxylic acid group suitable for coupling with amines through amide bond formation. The PEG2 spacer enhances solubility, provides flexibility, and reduces steric hindrance in conjugates, making it ideal for bioconjugation applications. This reagent is widely used in peptide and protein modification, drug delivery system development, antibody–drug conjugates (ADCs), and biomaterial functionalization. Boc-NH-PEG2-CH2CH2COOH serves as a reliable tool for controlled PEGylation and advanced chemical biology research.