Boc-N-methyl-L-isoleucine

• CAT Number: I043249
• CAS Number: 52498-32-5
• Molecular Formula: C12H23NO4
• Molecular Weight: 245.32
• Purity: ≥95%
• Synonyms: (2S,3S)-3-methyl-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]pentanoic acid
• InChI: InChI=1S/C12H23NO4/c1-7-8(2)9(10(14)15)13(6)11(16)17-12(3,4)5/h8-9H,7H2,1-6H3,(H,14,15)/t8-,9-/m0/s1
• InChIKey: HTBIAUMDQYXOFG-IUCAKERBSA-N
• SMILES: CC[C@H](C)[C@@H](C(=O)O)N(C)C(=O)OC(C)(C)C

Boc-N-methyl-L-isoleucine（Cat No.:I043249）is a derivative of L-isoleucine where the N-terminal amine group is protected by a tert-butoxycarbonyl (Boc) group, and the amino group of isoleucine is methylated to form N-methyl-L-isoleucine. This modification prevents unwanted side reactions during peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). The Boc group allows selective deprotection during peptide elongation, while the N-methyl group introduces steric and electronic changes that can impact peptide conformation, stability, and hydrophobicity. This compound is used to synthesize modified peptides for research in drug development and bioactive peptide studies.