Boc-Glu-OtBu

• CAT Number: R034560
• CAS Number: 24277-39-2
• Molecular Formula: C14H25NO6
• Molecular Weight: 303.35
• Purity: ≥95%
• Synonyms: (4S)-5-[(2-methylpropan-2-yl)oxy]-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxopentanoic acid
• InChI: InChI=1S/C14H25NO6/c1-13(2,3)20-11(18)9(7-8-10(16)17)15-12(19)21-14(4,5)6/h9H,7-8H2,1-6H3,(H,15,19)(H,16,17)/t9-/m0/s1
• InChIKey: YMOYURYWGUWMFM-VIFPVBQESA-N
• SMILES: CC(C)(C)OC(=O)[C@H](CCC(=O)O)NC(=O)OC(C)(C)C

Boc-Glu-OtBu（Cat No.:R034560）is a protected derivative of glutamic acid (Glu), where the N-terminal amine group is protected by a tert-butoxycarbonyl (Boc) group, and the carboxyl group at the side chain is esterified with a tert-butyl (OtBu) group. This modification is commonly used in peptide synthesis to prevent side reactions, especially during solid-phase peptide synthesis (SPPS). The Boc protection allows for selective deprotection of the amine group, while the tBu ester enhances the stability and solubility of the glutamic acid residue, making it useful for the synthesis of bioactive peptides and pharmaceutical applications.