Boc-aminooxy-PEG2-propargyl

• CAT Number: I016142
• CAS Number: 1895922-74-3
• Molecular Formula: C12H21NO5
• Molecular Weight: 259.30
• Purity: ≥95%
• Synonyms: tert-butyl N-[2-(2-prop-2-ynoxyethoxy)ethoxy]carbamate
• InChI: InChI=1S/C12H21NO5/c1-5-6-15-7-8-16-9-10-17-13-11(14)18-12(2,3)4/h1H,6-10H2,2-4H3,(H,13,14)
• InChIKey: XXPUFYWATPLMHN-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)NOCCOCCOCC#C

Boc-aminooxy-PEG2-propargyl（Cat No.:I016142）is a multifunctional linker designed for orthogonal and selective bioconjugation. It features a Boc-protected aminooxy group that, upon deprotection, enables oxime ligation with aldehydes or ketones, forming stable linkages. The terminal propargyl group supports click chemistry with azides via copper-catalyzed or strain-promoted reactions, allowing dual reactivity. The PEG2 spacer enhances solubility, flexibility, and reduces steric hindrance, ensuring efficient coupling in biological systems. This reagent is highly valuable for constructing multifunctional conjugates in drug delivery, diagnostic probe development, chemical biology, and advanced material science where modular assembly is essential.