Boc-Aminooxy-PEG2-C2-amine

• CAT Number: I014705
• CAS Number: 252378-69-1
• Molecular Formula: C11H24N2O5
• Molecular Weight: 264.32
• Purity: ≥95%
• Synonyms: tert-butyl N-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]carbamate
• InChI: InChI=1S/C11H24N2O5/c1-11(2,3)18-10(14)13-17-9-8-16-7-6-15-5-4-12/h4-9,12H2,1-3H3,(H,13,14)
• InChIKey: LHNRKSSHYXYKTA-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)NOCCOCCOCCN

Boc-Aminooxy-PEG2-C2-amine（Cat No.:I014705）is a bifunctional PEG-based linker featuring a Boc-protected aminooxy group and a free terminal amine, separated by a two-unit PEG chain and a two-carbon (C2) spacer. The aminooxy group, once deprotected, enables chemoselective oxime or hydrazone ligation with aldehydes and ketones, while the amine group facilitates amide bond formation with carboxylic acids. The PEG2-C2 structure enhances solubility, provides flexibility, and minimizes steric hindrance, ensuring efficient conjugation. This versatile reagent is widely used in bioconjugation, peptide synthesis, and drug discovery for constructing multifunctional biomolecules and therapeutic platforms.