For research use only. Not for therapeutic Use.
BNC375（Cat No.:I018993）is a novel, selective positive allosteric modulator (PAM) of the α7 nicotinic acetylcholine receptor (α7 nAChR), a receptor implicated in cognitive processes, neuroinflammation, and synaptic plasticity. By enhancing receptor responsiveness to acetylcholine without directly activating it, BNC375 improves neuronal signaling with reduced risk of receptor desensitization. It has been studied for potential therapeutic benefits in Alzheimer’s disease, schizophrenia, and other cognitive disorders. BNC375 is widely applied in neuroscience research as a tool to investigate α7 nAChR biology, cognition enhancement, and neuropsychiatric drug discovery.
| CAS Number | 1557240-80-8 |
| Synonyms | 4-[(1R,3R)-3-[(5-chloro-2-methoxyanilino)methyl]-2,2-dimethylcyclopropyl]benzenesulfonamide |
| Molecular Formula | C19H23ClN2O3S |
| Purity | ≥95% |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
