For research use only. Not for therapeutic Use.
BMS-P5 free base（Cat No.:I023563）is a potent stimulator of STING (stimulator of interferon genes), a critical adaptor protein in the innate immune response. By binding to the STING protein, BMS-P5 activates downstream signaling pathways leading to the production of type I interferons and proinflammatory cytokines. This immune activation is particularly valuable in cancer immunotherapy and antiviral research. As a non-cyclic dinucleotide STING agonist, BMS-P5 free base offers improved drug-like properties and cellular permeability. It is widely used in preclinical studies to evaluate immune modulation and enhance antitumor immune responses.
| CAS Number | 1550371-22-6 |
| Synonyms | [(2S,5R)-5-amino-2-methylpiperidin-1-yl]-[2-[1-(cyclopropylmethyl)pyrrolo[2,3-b]pyridin-2-yl]-7-methoxy-1-methylbenzimidazol-5-yl]methanone |
| Molecular Formula | C27H32N6O2 |
| Purity | ≥95% |
| IUPAC Name | [(2S,5R)-5-amino-2-methylpiperidin-1-yl]-[2-[1-(cyclopropylmethyl)pyrrolo[2,3-b]pyridin-2-yl]-7-methoxy-1-methylbenzimidazol-5-yl]methanone |
| InChI | InChI=1S/C27H32N6O2/c1-16-6-9-20(28)15-32(16)27(34)19-11-21-24(23(13-19)35-3)31(2)26(30-21)22-12-18-5-4-10-29-25(18)33(22)14-17-7-8-17/h4-5,10-13,16-17,20H,6-9,14-15,28H2,1-3H3/t16-,20+/m0/s1 |
| InChIKey | PXJXCBYHGJEEJH-OXJNMPFZSA-N |
| SMILES | C[C@H]1CC[C@H](CN1C(=O)C2=CC3=C(C(=C2)OC)N(C(=N3)C4=CC5=C(N4CC6CC6)N=CC=C5)C)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
