For research use only. Not for therapeutic Use.
BMS CCR2 22(Cat No.:I010705)is a potent and selective small-molecule antagonist of the C-C chemokine receptor type 2 (CCR2), a receptor involved in monocyte recruitment, inflammation, and tumor progression. By blocking CCR2 signaling, this compound interferes with CCL2-mediated chemotaxis, offering a valuable tool for studying immune cell trafficking, chronic inflammation, and cancer metastasis. It has been employed in preclinical research exploring therapeutic strategies for autoimmune disease, fibrosis, and oncology. Supplied as a research reagent, BMS CCR2 22 is intended exclusively for laboratory use, not for clinical applications.
CAS Number | 445479-97-0 |
Synonyms | N-[2-[[(1S,2R)-2-[(4-methylsulfanylbenzoyl)amino]cyclohexyl]amino]-2-oxoethyl]-2-(propan-2-ylcarbamoylamino)-5-(trifluoromethyl)benzamide |
Molecular Formula | C28H34F3N5O4S |
Purity | ≥95% |
IUPAC Name | N-[2-[[(1R,2S)-2-[(4-methylsulfanylbenzoyl)amino]cyclohexyl]amino]-2-oxoethyl]-2-(propan-2-ylcarbamoylamino)-5-(trifluoromethyl)benzamide |
InChI | InChI=1S/C28H34F3N5O4S/c1-16(2)33-27(40)36-21-13-10-18(28(29,30)31)14-20(21)26(39)32-15-24(37)34-22-6-4-5-7-23(22)35-25(38)17-8-11-19(41-3)12-9-17/h8-14,16,22-23H,4-7,15H2,1-3H3,(H,32,39)(H,34,37)(H,35,38)(H2,33,36,40)/t22-,23+/m1/s1 |
InChIKey | IBPXYDUJQWENPM-PKTZIBPZSA-N |
SMILES | CC(C)NC(=O)NC1=C(C=C(C=C1)C(F)(F)F)C(=O)NCC(=O)N[C@@H]2CCCC[C@@H]2NC(=O)C3=CC=C(C=C3)SC |
Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |