For research use only. Not for therapeutic Use.
BMS-986187（Cat No.:R030164）is a potent, positive allosteric modulator (PAM) of the μ-opioid receptor (MOR), designed to enhance the efficacy of opioid agonists like morphine without directly activating the receptor itself. By binding to an allosteric site, BMS-986187 amplifies opioid signaling, allowing for lower doses of opioids to achieve effective analgesia. This modulation aims to reduce side effects such as respiratory depression, tolerance, and dependence commonly associated with traditional opioids. BMS-986187 is a promising compound in pain management research, supporting the development of safer, more effective opioid-based therapies.
| CAS Number | 684238-37-7 |
| Synonyms | 3,3,6,6-tetramethyl-9-[4-[(2-methylphenyl)methoxy]phenyl]-4,5,7,9-tetrahydro-2H-xanthene-1,8-dione |
| Molecular Formula | C31H34O4 |
| Purity | ≥95% |
| IUPAC Name | 3,3,6,6-tetramethyl-9-[4-[(2-methylphenyl)methoxy]phenyl]-4,5,7,9-tetrahydro-2H-xanthene-1,8-dione |
| InChI | InChI=1S/C31H34O4/c1-19-8-6-7-9-21(19)18-34-22-12-10-20(11-13-22)27-28-23(32)14-30(2,3)16-25(28)35-26-17-31(4,5)15-24(33)29(26)27/h6-13,27H,14-18H2,1-5H3 |
| InChIKey | UEKIYVKPQNKSDI-UHFFFAOYSA-N |
| SMILES | CC1=CC=CC=C1COC2=CC=C(C=C2)C3C4=C(CC(CC4=O)(C)C)OC5=C3C(=O)CC(C5)(C)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
