BLI-489 hydrate（Cat No.:I045881）is a potent inhibitor of β-lactamases, enzymes responsible for bacterial resistance to β-lactam antibiotics. By blocking β-lactamase activity, it restores the antibacterial efficacy of penicillins, cephalosporins, and carbapenems against resistant pathogens. Supplied as a hydrate form for stability and handling, BLI-489 is valuable in antimicrobial research, particularly in studies of multidrug-resistant Gram-negative bacteria. It serves as a tool for investigating resistance mechanisms and evaluating novel β-lactam/β-lactamase inhibitor combinations, supporting the development of therapeutic strategies to combat antibiotic resistance and improve clinical treatment outcomes.