For research use only. Not for therapeutic Use.
Blasticidin S hydrochloride (Cat No.: R024204) is a potent antibiotic and protein synthesis inhibitor derived from Streptomyces griseochromogenes. It targets both prokaryotic and eukaryotic ribosomes by interfering with peptide bond formation during translation. Widely used in molecular biology, it serves as a selective agent for the maintenance of plasmids or transgenes containing the bsd resistance gene. Its rapid action and broad-spectrum activity make it ideal for cell culture applications, including gene expression studies, stable cell line generation, and functional genomics in bacteria, yeast, and mammalian cells.
CAS Number | 3513-03-9 |
Synonyms | Blasticidin S Monohydrochloride; (S)-4-[[3-Amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-β-D-erythro-Hex-2-enopyranuronic Acid Monohydrochloride; |
Molecular Formula | C₁₇H₂₆N₈O₅ · HCl |
Purity | ≥95% |
Target | DNA Synthesis |
Solubility | Limited solubility |
Appearance | White solid |
Storage | Store at -20°C |
IUPAC Name | (2S,3S,6R)-3-[[(3R)-3-amino-5-[carbamimidoyl(methyl)amino]pentanoyl]amino]-6-(4-amino-2-oxopyrimidin-1-yl)-3,6-dihydro-2H-pyran-2-carboxylic acid;hydrochloride |
InChI | InChI=1S/C17H26N8O5.ClH/c1-24(16(20)21)6-4-9(18)8-12(26)22-10-2-3-13(30-14(10)15(27)28)25-7-5-11(19)23-17(25)29;/h2-3,5,7,9-10,13-14H,4,6,8,18H2,1H3,(H3,20,21)(H,22,26)(H,27,28)(H2,19,23,29);1H/t9-,10+,13-,14+;/m1./s1 |
InChIKey | YQXYQOXRCNEATG-ZAYJLJTISA-N |
SMILES | CN(CCC(CC(=O)NC1C=CC(OC1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N.Cl |
Reference | <p> |
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