Bisindolylmaleimide II

• CAT Number: I010898
• CAS Number: 137592-45-1
• Molecular Formula: C27H26N4O2
• Molecular Weight: 438.52
• Purity: ≥95%
• Synonyms: 3-(1H-indol-3-yl)-4-[1-[2-(1-methylpyrrolidin-2-yl)ethyl]indol-3-yl]pyrrole-2,5-dione
• InChI: InChI=1S/C27H26N4O2/c1-30-13-6-7-17(30)12-14-31-16-21(19-9-3-5-11-23(19)31)25-24(26(32)29-27(25)33)20-15-28-22-10-4-2-8-18(20)22/h2-5,8-11,15-17,28H,6-7,12-14H2,1H3,(H,29,32,33)
• InChIKey: LBFDERUQORUFIN-UHFFFAOYSA-N
• SMILES: CN1CCCC1CCN2C=C(C3=CC=CC=C32)C4=C(C(=O)NC4=O)C5=CNC6=CC=CC=C65

Bisindolylmaleimide II（Cat No.:I010898）is a potent, selective inhibitor of protein kinase C (PKC), a family of enzymes involved in regulating various cellular processes such as cell growth, differentiation, and apoptosis. By inhibiting PKC, Bisindolylmaleimide II can interfere with signaling pathways that contribute to cancer cell proliferation and survival. It has shown promise in preclinical studies as a potential therapeutic agent for treating cancers, as well as in conditions involving abnormal cell signaling. Further clinical research is needed to assess its safety, effectiveness, and potential in cancer therapy and other diseases associated with PKC dysregulation.