Bis-propargyl-PEG5

• CAT Number: I045983
• CAS Number: 185378-83-0
• Molecular Formula: C16H26O6
• Molecular Weight: 314.37
• Purity: ≥95%
• Synonyms: 3-[2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]prop-1-yne
• InChI: InChI=1S/C16H26O6/c1-3-5-17-7-9-19-11-13-21-15-16-22-14-12-20-10-8-18-6-4-2/h1-2H,5-16H2
• InChIKey: UDOWAMKIEUIBMU-UHFFFAOYSA-N
• SMILES: C#CCOCCOCCOCCOCCOCCOCC#C

Bis-propargyl-PEG5(CAT: I045983) is a homobifunctional polyethylene glycol (PEG) linker featuring terminal propargyl (alkyne) groups at both ends of a five-unit PEG spacer. The alkyne moieties enable efficient azide–alkyne cycloaddition (“click chemistry”), allowing the formation of stable triazole linkages with azide-containing molecules. The PEG5 chain imparts hydrophilicity, flexibility, and reduced steric hindrance, ensuring enhanced solubility and biocompatibility. Bis-propargyl-PEG5 is a versatile tool for crosslinking, bioconjugation, polymer modification, and nanomaterials research, supporting the construction of multifunctional biomolecules and advanced drug delivery systems. Its symmetric design makes it ideal for preparing well-defined, dual-functionalized constructs in chemical biology and materials science.