Biotin-PEG8-acid

• CAT Number: I045980
• CAS Number: 2143964-62-7
• Molecular Formula: C29H53N3O12S
• Molecular Weight: 667.81
• Purity: ≥95%
• Synonyms: 3-[2-[2-[2-[2-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
• InChI: InChI=1S/C29H53N3O12S/c33-26(4-2-1-3-25-28-24(23-45-25)31-29(36)32-28)30-6-8-38-10-12-40-14-16-42-18-20-44-22-21-43-19-17-41-15-13-39-11-9-37-7-5-27(34)35/h24-25,28H,1-23H2,(H,30,33)(H,34,35)(H2,31,32,36)/t24-,25-,28-/m0/s1
• InChIKey: MPJWZTARMHIZLN-VBOOUTDYSA-N
• SMILES: C1C2C(C(S1)CCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O)NC(=O)N2

Biotin-PEG8-acid(CAT: I045980) is a biotinylated linker with a terminal carboxylic acid group and an extended PEG8 spacer. The carboxyl group can be activated for conjugation to primary amines, enabling stable amide bond formation with proteins, peptides, and other amine-containing molecules. The PEG8 chain improves aqueous solubility, reduces steric hindrance, and provides flexibility, enhancing coupling efficiency in bioconjugation reactions. The biotin tag ensures strong, specific interaction with streptavidin or avidin, facilitating detection, enrichment, and immobilization. Biotin-PEG8-acid is widely used in chemical biology, proteomics, diagnostics, and drug discovery applications requiring reliable biotinylation and affinity-based separation.