Biotin-PEG6-azide

• CAT Number: I016790
• CAS Number: 1085938-09-5
• Molecular Formula: C24H44N6O8S
• Molecular Weight: 576.71
• Purity: ≥95%
• Synonyms: 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]pentanamide
• InChI: InChI=1S/C24H44N6O8S/c25-30-27-6-8-34-10-12-36-14-16-38-18-17-37-15-13-35-11-9-33-7-5-26-22(31)4-2-1-3-21-23-20(19-39-21)28-24(32)29-23/h20-21,23H,1-19H2,(H,26,31)(H2,28,29,32)/t20-,21-,23-/m0/s1
• InChIKey: WTVVCWJIXLJVCQ-FUDKSRODSA-N
• SMILES: C1C2C(C(S1)CCCCC(=O)NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])NC(=O)N2

Biotin-PEG6-azide(CAT: I016790) is a biotinylated probe featuring a terminal azide group and a flexible PEG6 spacer. The azide functionality enables efficient copper-catalyzed azide–alkyne cycloaddition (CuAAC, “click chemistry”) with alkyne-containing molecules, forming stable triazole linkages. The PEG6 chain improves solubility, minimizes steric hindrance, and provides conformational flexibility, ensuring efficient bioconjugation. The biotin moiety allows strong, specific binding to streptavidin or avidin systems, supporting detection, affinity purification, and immobilization applications. Biotin-PEG6-azide is widely used in chemical biology, proteomics, and drug discovery research for labeling, biomolecular tracking, and constructing multifunctional probes via click chemistry.