For research use only. Not for therapeutic Use.
Biotin-PEG4-SH（Cat No.:I044547）is a biotinylated polyethylene glycol (PEG) linker terminated with a thiol (-SH) group, designed for versatile bioconjugation applications. The PEG4 spacer provides flexibility, water solubility, and reduced steric hindrance, enhancing the bioavailability and accessibility of the biotin moiety. The terminal thiol allows for selective conjugation to maleimide-activated or gold surfaces via thiol–maleimide or gold–thiol chemistry. Biotin-PEG4-SH is widely used in surface modification, nanoparticle functionalization, protein labeling, and affinity assays, facilitating streptavidin-based detection and purification with improved stability and reduced non-specific interactions in biological systems.
| CAS Number | 2762393-22-4 |
| Synonyms | 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]ethoxy]ethyl]pentanamide |
| Molecular Formula | C20H37N3O6S2 |
| Purity | ≥95% |
| IUPAC Name | 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]ethoxy]ethyl]pentanamide |
| InChI | InChI=1S/C20H37N3O6S2/c24-18(4-2-1-3-17-19-16(15-31-17)22-20(25)23-19)21-5-6-26-7-8-27-9-10-28-11-12-29-13-14-30/h16-17,19,30H,1-15H2,(H,21,24)(H2,22,23,25)/t16-,17-,19-/m0/s1 |
| InChIKey | NIJSULOOONHHJS-LNLFQRSKSA-N |
| SMILES | C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)NCCOCCOCCOCCOCCS)NC(=O)N2 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
