For research use only. Not for therapeutic Use.
Biotin-PEG4-Picolyl azide（Cat No.:I045910）is a highly efficient bioconjugation reagent that integrates a biotin moiety for strong streptavidin/avidin binding with a picolyl azide group for rapid, copper-catalyzed click chemistry. The picolyl azide enhances reaction kinetics and specificity compared to standard azides, enabling more efficient labeling. The PEG4 spacer provides hydrophilicity, flexibility, and reduced steric hindrance, improving solubility and biomolecular accessibility. This reagent is widely used in proteomics, imaging, affinity capture, and drug discovery applications, where fast, selective, and reliable bioconjugation is essential for studying complex biological systems.
| CAS Number | 2222687-71-8 |
| Synonyms | 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[2-[3-[[6-(azidomethyl)pyridin-3-yl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethyl]pentanamide |
| Molecular Formula | C27H42N8O7S |
| Purity | ≥95% |
| IUPAC Name | 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[2-[3-[[6-(azidomethyl)pyridin-3-yl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethyl]pentanamide |
| InChI | InChI=1S/C27H42N8O7S/c28-35-31-18-20-5-6-21(17-30-20)32-25(37)7-9-39-11-13-41-15-16-42-14-12-40-10-8-29-24(36)4-2-1-3-23-26-22(19-43-23)33-27(38)34-26/h5-6,17,22-23,26H,1-4,7-16,18-19H2,(H,29,36)(H,32,37)(H2,33,34,38)/t22-,23-,26-/m0/s1 |
| InChIKey | MIIHOWLWUTYJDT-FXSPECFOSA-N |
| SMILES | C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)NCCOCCOCCOCCOCCC(=O)NC3=CN=C(C=C3)CN=[N+]=[N-])NC(=O)N2 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
