For research use only. Not for therapeutic Use.
Biotin-PEG4-amino-t-Bu-DADPS-C3-alkyne（Cat No.:I015734）is a cleavable, multifunctional linker designed for advanced bioconjugation. It features a biotin moiety for strong streptavidin/avidin binding, a PEG4 spacer to enhance solubility and reduce steric hindrance, and an alkyne group for click chemistry with azides. The DADPS (dialkoxydiphenylsilane) unit introduces a chemically cleavable site, while the t-Bu-protected amine allows orthogonal deprotection and further derivatization. The C3 linker segment provides additional flexibility and spacing. This reagent is widely used in proteomics, targeted enrichment, chemical probe development, and drug discovery research.
| CAS Number | 2241685-22-1 |
| Synonyms | 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[2-[3-[[2-methyl-2-[pent-4-ynoxy(diphenyl)silyl]oxypropyl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethyl]pentanamide |
| Molecular Formula | C42H62N4O9SSi |
| Purity | ≥95% |
| IUPAC Name | 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[2-[3-[[2-methyl-2-[pent-4-ynoxy(diphenyl)silyl]oxypropyl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethyl]pentanamide |
| InChI | InChI=1S/C42H62N4O9SSi/c1-4-5-14-23-54-57(34-15-8-6-9-16-34,35-17-10-7-11-18-35)55-42(2,3)33-44-39(48)21-24-50-26-28-52-30-31-53-29-27-51-25-22-43-38(47)20-13-12-19-37-40-36(32-56-37)45-41(49)46-40/h1,6-11,15-18,36-37,40H,5,12-14,19-33H2,2-3H3,(H,43,47)(H,44,48)(H2,45,46,49)/t36-,37-,40-/m0/s1 |
| InChIKey | DJUQDDBYPFLTPN-HKGQQODZSA-N |
| SMILES | CC(C)(CNC(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@H]1[C@@H]2[C@H](CS1)NC(=O)N2)O[Si](C3=CC=CC=C3)(C4=CC=CC=C4)OCCCC#C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
