For research use only. Not for therapeutic Use.
Biotin-PEG3-Mal(CAT: I014200) is a biotinylated probe featuring a maleimide group and a short PEG3 spacer. The maleimide moiety reacts selectively with sulfhydryl groups on cysteine residues, enabling site-specific conjugation to peptides, proteins, and other thiol-containing molecules. The PEG3 linker enhances solubility, provides flexibility, and reduces steric hindrance, ensuring efficient bioconjugation. The biotin tag offers strong affinity for streptavidin and avidin systems, supporting sensitive detection, immobilization, and affinity purification. Biotin-PEG3-Mal is widely used in chemical biology, proteomics, and drug discovery for labeling, pull-down assays, and protein interaction studies where selective thiol-reactive biotinylation is required.
| CAS Number | 1431618-70-0 |
| Synonyms | 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethyl]pentanamide |
| Molecular Formula | C25H39N5O8S |
| Purity | ≥95% |
| IUPAC Name | 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethyl]pentanamide |
| InChI | InChI=1S/C25H39N5O8S/c31-20(4-2-1-3-19-24-18(17-39-19)28-25(35)29-24)26-8-11-36-13-15-38-16-14-37-12-9-27-21(32)7-10-30-22(33)5-6-23(30)34/h5-6,18-19,24H,1-4,7-17H2,(H,26,31)(H,27,32)(H2,28,29,35)/t18-,19-,24-/m0/s1 |
| InChIKey | OSIQQRWDJZNBFW-JXQFQVJHSA-N |
| SMILES | C1C2C(C(S1)CCCCC(=O)NCCOCCOCCOCCNC(=O)CCN3C(=O)C=CC3=O)NC(=O)N2 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
