Biotin-PEG2-C6-azide

• CAT Number: I014190
• CAS Number: 1011268-29-3
• Molecular Formula: C22H39N7O5S
• Molecular Weight: 513.65
• Purity: ≥95%
• Synonyms: N-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethyl]-6-azidohexanamide
• InChI: InChI=1S/C22H39N7O5S/c23-29-26-9-5-1-2-7-19(30)24-10-12-33-14-15-34-13-11-25-20(31)8-4-3-6-18-21-17(16-35-18)27-22(32)28-21/h17-18,21H,1-16H2,(H,24,30)(H,25,31)(H2,27,28,32)/t17-,18-,21-/m0/s1
• InChIKey: NYAZUAAGKILBHO-WFXMLNOXSA-N
• SMILES: C1C2C(C(S1)CCCCC(=O)NCCOCCOCCNC(=O)CCCCCN=[N+]=[N-])NC(=O)N2

Biotin-PEG2-C6-azide(CAT: I014190) is a versatile biotinylated linker designed for click chemistry applications. It features a terminal azide group, enabling efficient copper-catalyzed azide–alkyne cycloaddition (CuAAC) with alkyne-functionalized molecules. The PEG2 spacer improves solubility, flexibility, and minimizes steric hindrance, while the C6 alkyl chain provides additional length for optimal spatial orientation in conjugation strategies. Biotin-PEG2-C6-azide is widely used for bioconjugation, affinity labeling, pull-down assays, and immobilization of biomolecules on streptavidin/avidin surfaces. Its design ensures high-performance in protein labeling, drug discovery, chemical biology, and diagnostic research, making it an essential reagent for precise biomolecular modification and functionalization.