Bim-IN-1

For research use only. Not for therapeutic Use.

  • CAT Number: I044124
  • CAS Number: 2909483-36-7
  • Molecular Formula: C19H20Cl2FNO2S
  • Molecular Weight: 416.34
  • Purity: ≥95%
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Bim-IN-1(Cat No.:I044124)is a selective inhibitor targeting the pro-apoptotic protein Bim, a member of the Bcl-2 family involved in mitochondrial-mediated apoptosis. By disrupting Bim’s interaction with anti-apoptotic proteins like Bcl-2 and Bcl-xL, Bim-IN-1 modulates intrinsic apoptotic signaling, thereby influencing cell survival. It is a valuable tool for studying apoptosis regulation in cancer, neurodegenerative diseases, and immune responses. Bim-IN-1 helps researchers explore mechanisms of chemoresistance and assess therapeutic strategies that involve apoptosis modulation. Its specificity offers insights into Bim-driven cell death pathways and their potential as drug targets.


CAS Number 2909483-36-7
Synonyms

1-[(2,4-dichlorophenyl)methylsulfonyl]-2-(3-fluorophenyl)azepane

Molecular Formula C19H20Cl2FNO2S
Purity ≥95%
IUPAC Name 1-[(2,4-dichlorophenyl)methylsulfonyl]-2-(3-fluorophenyl)azepane
InChI InChI=1S/C19H20Cl2FNO2S/c20-16-9-8-15(18(21)12-16)13-26(24,25)23-10-3-1-2-7-19(23)14-5-4-6-17(22)11-14/h4-6,8-9,11-12,19H,1-3,7,10,13H2
InChIKey SFVNBTZMJWQDLM-UHFFFAOYSA-N
SMILES C1CCC(N(CC1)S(=O)(=O)CC2=C(C=C(C=C2)Cl)Cl)C3=CC(=CC=C3)F
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