Biguanide

• CAT Number: I023383
• CAS Number: 56-03-1
• Molecular Formula: C2H7N5
• Molecular Weight: 101.11
• Purity: 98%
• Synonyms: AI3-52571; AI3 52571; AI352571; Biguanide
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: Biguanide
• InChI: InChI=1S/C2H7N5/c3-1(4)7-2(5)6/h(H7,3,4,5,6,7)
• InChIKey: XNCOSPRUTUOJCJ-UHFFFAOYSA-N
• SMILES: NC(NC(N)=N)=N

Biguanide (Cat No.: I023383) refers to a chemical class of compounds characterized by two linked guanidine groups. The most well-known member is metformin, a first-line oral antidiabetic drug used to manage type 2 diabetes. Biguanides work primarily by decreasing hepatic glucose production, improving insulin sensitivity, and enhancing peripheral glucose uptake. They may also exhibit potential anticancer and antimicrobial properties. While effective, older biguanides like phenformin were withdrawn due to lactic acidosis risk. Modern biguanides, especially metformin, are widely used and generally well-tolerated.