For research use only. Not for therapeutic Use.
BIBP3226 TFA(Cat No.:I011694)is a potent, selective, non-peptide antagonist of the neuropeptide Y (NPY) Y1 receptor. By blocking Y1 receptor signaling, it has been widely used to investigate the physiological and pathological roles of NPY in feeding behavior, anxiety, cardiovascular regulation, and energy balance. The trifluoroacetate (TFA) salt form improves stability and handling in experimental applications. BIBP3226 TFA serves as a valuable pharmacological tool in neuroscience, endocrinology, and metabolic disease research, enabling exploration of NPY receptor pathways and the development of targeted therapeutic strategies.
CAS Number | 1068148-47-9 |
Synonyms | (2R)-5-(diaminomethylideneamino)-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide;2,2,2-trifluoroacetic acid |
Molecular Formula | C29H32F3N5O5 |
Purity | ≥95% |
IUPAC Name | (2R)-5-(diaminomethylideneamino)-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide;2,2,2-trifluoroacetic acid |
InChI | InChI=1S/C27H31N5O3.C2HF3O2/c28-27(29)30-17-7-12-23(25(34)31-18-19-13-15-22(33)16-14-19)32-26(35)24(20-8-3-1-4-9-20)21-10-5-2-6-11-21;3-2(4,5)1(6)7/h1-6,8-11,13-16,23-24,33H,7,12,17-18H2,(H,31,34)(H,32,35)(H4,28,29,30);(H,6,7)/t23-;/m1./s1 |
InChIKey | MTSZIDSCWZHKOD-GNAFDRTKSA-N |
SMILES | C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)N[C@H](CCCN=C(N)N)C(=O)NCC3=CC=C(C=C3)O.C(=O)(C(F)(F)F)O |
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