For research use only. Not for therapeutic Use.
BI-1935(CAT:I017412) is a potent and selective inhibitor of soluble epoxide hydrolase (sEH), an enzyme that metabolizes epoxyeicosatrienoic acids (EETs) into less active diols. By blocking sEH activity, BI-1935 enhances the biological effects of EETs, including vasodilation, anti-inflammatory, and cardioprotective actions. This compound represents a valuable pharmacological tool for studying the role of sEH in vascular regulation, inflammation, and metabolic processes. BI-1935 is particularly useful in cardiovascular disease research, offering insights into therapeutic strategies targeting sEH inhibition for hypertension, ischemia, and related disorders.
| CAS Number | 940954-41-6 |
| Molecular Formula | C24H21F3N6O3 |
| Purity | ≥95% |
| IUPAC Name | 1-(2-ethoxyethyl)-6-oxo-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide |
| InChI | InChI=1S/C24H21F3N6O3/c1-2-36-11-10-32-15-17(5-8-22(32)34)23(35)30-21-7-6-18(14-29-21)33-20(24(25,26)27)12-19(31-33)16-4-3-9-28-13-16/h3-9,12-15H,2,10-11H2,1H3,(H,29,30,35) |
| InChIKey | KMESAVNRPDKZCQ-UHFFFAOYSA-N |
| SMILES | CCOCCN1C=C(C=CC1=O)C(=O)NC2=NC=C(C=C2)N3C(=CC(=N3)C4=CN=CC=C4)C(F)(F)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
