Betamethasone Valerate

• CAT Number: A000941
• CAS Number: 2152-44-5
• Molecular Formula: C27H37FO6
• Molecular Weight: 476.58
• Purity: ≥95%
• Synonyms: Betnovate; Betamethasone 17-valerate; Betaderm; Luxiq; 2152-44-5
• Target: Vitamin D Related/Nuclear Receptor
• Storage: -20°C
• IUPAC Name: [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] pentanoate
• InChI: 1S/C27H37FO6/c1-5-6-7-23(33)34-27(22(32)15-29)16(2)12-20-19-9-8-17-13-18(30)10-11-24(17,3)26(19,28)21(31)14-25(20,27)4/h10-11,13,16,19-21,29,31H,5-9,12,14-15H2,1-4H3/t16-,19-,20-,21-,24-,25-,26-,27-/m0/s1
• InChIKey: SNHRLVCMMWUAJD-SUYDQAKGSA-N
• SMILES: CCCCC(=O)OC1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)C(=O)CO

Betamethasone valerate (Cat No.: A000941) is a medium- to high-potency corticosteroid used topically to treat inflammatory and pruritic skin conditions such as eczema, psoriasis, and dermatitis. It reduces inflammation, redness, and itching by inhibiting the release of inflammatory mediators and suppressing immune responses. Available in creams, ointments, lotions, and foams, it is applied in thin layers to affected areas. Prolonged use may cause local side effects like skin thinning, irritation, or telangiectasia, and systemic absorption risks increase with extensive or occlusive application.

Reference

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