For research use only. Not for therapeutic Use.
Betamethasone dipropionate (Cat No.: A000937) is a potent synthetic corticosteroid used topically to treat inflammatory skin conditions such as eczema, psoriasis, and dermatitis. It works by suppressing inflammation, immune responses, and itching through inhibition of cytokine production and leukocyte migration. Available in creams, ointments, and lotions, it provides rapid relief from redness, swelling, and irritation. Prolonged use may cause skin thinning, discoloration, or systemic absorption leading to adrenal suppression. It should be used as directed, especially in children and on sensitive skin areas.
CAS Number | 5593-20-4 |
Synonyms | Diprosone; Diprolene; Diprolene AF; Diproderm; Maxivate |
Molecular Formula | C28H37FO7 |
Purity | ≥95% |
Target | Vitamin D Related/Nuclear Receptor |
Storage | -20°C |
IUPAC Name | [2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate |
InChI | 1S/C28H37FO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1 |
InChIKey | CIWBQSYVNNPZIQ-XYWKZLDCSA-N |
SMILES | CCC(=O)OCC(=O)C1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)OC(=O)CC |
Reference | 1: Morita A, Muramatsu S, Kubo R, Ikumi K, Sagawa Y, Saito C, Torii K, Nishida E. 2: Patel NU, Felix K, Reimer D, Feldman SR. Calcipotriene/betamethasone <br> <br> 5: Frieder J, Kivelevitch D, Menter A. Calcipotriene betamethasone dipropionate <br> <br> 8: Paul C, Leonardi C, Menter A, Reich K, Gold LS, Warren RB, Møller A, Lebwohl 9: Menter A, Gold LS, Koo J, Villumsen J, Rosén M, Lebwohl M. Fixed-Combination 10: Paul C, Leonardi C, Menter A, Reich K, Gold LS, Warren RB, Møller A, Lebwohl |
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