For research use only. Not for therapeutic Use.
Benzyl-PEG4-THP (Cat No.: I045418) is a heterobifunctional polyethylene glycol (PEG) linker composed of four ethylene glycol units, providing hydrophilicity, flexibility, and reduced steric hindrance. It features a benzyl group, useful for hydrophobic interactions or as a protecting/anchoring moiety, and a tetrahydropyranyl (THP) group, which serves as an acid-labile protecting group for hydroxyl functionalities. The PEG4 spacer enhances solubility in aqueous and organic systems, making this reagent suitable for bioconjugation, drug delivery system development, and surface or polymer modification in chemical, pharmaceutical, and biomedical research applications.
| CAS Number | 1027926-86-8 |
| Synonyms | 2-[2-[2-[2-(2-phenylmethoxyethoxy)ethoxy]ethoxy]ethoxy]oxane |
| Molecular Formula | C20H32O6 |
| Purity | ≥95% |
| InChI | InChI=1S/C20H32O6/c1-2-6-19(7-3-1)18-24-15-14-22-11-10-21-12-13-23-16-17-26-20-8-4-5-9-25-20/h1-3,6-7,20H,4-5,8-18H2 |
| InChIKey | KNXMANKMVQASTE-UHFFFAOYSA-N |
| SMILES | C1CCOC(C1)OCCOCCOCCOCCOCC2=CC=CC=C2 |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
