Benzyl 2-cyclopropyl-2-hydroxyacetate

• CAT Number: I040494
• CAS Number: 182747-31-5
• Molecular Formula: C12H14O3
• Molecular Weight: 206.24
• Purity: ≥95%
• Synonyms: benzyl 2-cyclopropyl-2-hydroxyacetate
• InChI: InChI=1S/C12H14O3/c13-11(10-6-7-10)12(14)15-8-9-4-2-1-3-5-9/h1-5,10-11,13H,6-8H2
• InChIKey: HBEZCBDGJMYNGS-UHFFFAOYSA-N
• SMILES: C1CC1C(C(=O)OCC2=CC=CC=C2)O

Benzyl 2-cyclopropyl-2-hydroxyacetate(CAT: I040494) is a key intermediate used in the synthesis of antibody-drug conjugate (ADC) linkers. Its structure features a benzyl ester and a cyclopropyl-substituted hydroxyacetate core, offering functional versatility for conjugation strategies. This compound enables efficient coupling to cytotoxic payloads such as Exatecan (HY-13631), facilitating the assembly of stable and selective ADCs. When combined with antibodies like hu2F7, the resulting conjugates can deliver targeted anticancer activity with enhanced therapeutic indices. Benzyl 2-cyclopropyl-2-hydroxyacetate is ideal for researchers developing advanced linker-payload systems for ADC design. Supplied in high purity for use in medicinal chemistry and bioconjugation applications.