Benzethonium Chloride

• CAT Number: A000596
• CAS Number: 121-54-0
• Molecular Formula: C27H42NO2.Cl
• Molecular Weight: 448.08
• Purity: ≥95%
• Target: Neuronal Signaling
• Storage: Store at -20°C
• IUPAC Name: benzyl-dimethyl-[2-[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl]azanium;chloride
• InChI: InChI=1S/C27H42NO2.ClH/c1-26(2,3)22-27(4,5)24-13-15-25(16-14-24)30-20-19-29-18-17-28(6,7)21-23-11-9-8-10-12-23;/h8-16H,17-22H2,1-7H3;1H/q+1;/p-1
• InChIKey: UREZNYTWGJKWBI-UHFFFAOYSA-M
• SMILES: CC(C)(C)CC(C)(C)C1=CC=C(C=C1)OCCOCC[N+](C)(C)CC2=CC=CC=C2.[Cl-]

Benzethonium chloride（Cat No.:A000596）is a synthetic quaternary ammonium compound widely used as a topical antimicrobial and surfactant. With strong bactericidal and fungicidal properties, it is commonly found in antiseptics, mouthwashes, hand sanitizers, and personal care products. It disrupts microbial cell membranes, leading to cell death, making it effective against a broad spectrum of pathogens. In addition to its antimicrobial role, it also serves as a preservative and conditioning agent. Benzethonium chloride is valued for its long-lasting residual activity, stability in formulations, and low skin irritation at appropriate concentrations.

Reference

1.Tezcan, Filiz, et al. "Biocomposite films based on alginate and organically modified clay." International journal of biological macromolecules 50.4 (2012): 1165-1168.
2.Shamsudin, M. N., et al. "High prevalence of qacA/B carriage among clinical isolates of meticillin-resistant Staphylococcus aureus in Malaysia." Journal of Hospital Infection 81.3 (2012): 206-208.
3.Dao Jr, Harry, Chris Fricker, and Susan T. Nedorost. "Sensitization prevalence for benzalkonium chloride and benzethonium chloride." Dermatitis 23.4 (2012): 162-166.