Bendroflumethiazide

• CAT Number: R048737
• CAS Number: 73-48-3
• Molecular Formula: C15H14F3N3O4S2
• Molecular Weight: 421.41
• Purity: ≥95%
• Synonyms: 3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
• IUPAC Name: 3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide
• InChI: InChI=1S/C15H14F3N3O4S2/c16-15(17,18)10-7-11-13(8-12(10)26(19,22)23)27(24,25)21-14(20-11)6-9-4-2-1-3-5-9/h1-5,7-8,14,20-21H,6H2,(H2,19,22,23)
• InChIKey: HDWIHXWEUNVBIY-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)CC2NC3=C(C=C(C(=C3)C(F)(F)F)S(=O)(=O)N)S(=O)(=O)N2

Bendroflumethiazide（Cat No.:R048737）is a thiazide diuretic commonly used to treat hypertension and fluid retention associated with heart failure, liver cirrhosis, or renal disorders. It works by inhibiting sodium and chloride reabsorption in the distal convoluted tubules of the kidney, promoting increased excretion of sodium, water, and potassium. This diuretic action reduces blood volume and lowers blood pressure. Bendroflumethiazide also exhibits mild vasodilatory effects, contributing to its antihypertensive properties. It is typically administered orally and may cause side effects like electrolyte imbalance, dizziness, or increased blood glucose and uric acid levels.