Benazepril Hydrochloride

• CAT Number: A000228
• CAS Number: 86541-74-4
• Molecular Formula: C24H29ClN2O5
• Molecular Weight: 460.95
• Purity: ≥95%
• Synonyms: Benazepril HCl; 86541-74-4; Lotensin; Cibacene; Briem
• Target: Angiotensin-converting Enzyme (ACE)
• Storage: -20°C
• IUPAC Name: 2-[(3S)-3-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid;hydrochloride
• InChI: 1S/C24H28N2O5.ClH/c1-2-31-24(30)20(14-12-17-8-4-3-5-9-17)25-19-15-13-18-10-6-7-11-21(18)26(23(19)29)16-22(27)28;/h3-11,19-20,25H,2,12-16H2,1H3,(H,27,28);1H/t19-,20-;/m0./s1
• InChIKey: VPSRQEHTHIMDQM-FKLPMGAJSA-N
• SMILES: CCOC(=O)C(CCC1=CC=CC=C1)NC2CCC3=CC=CC=C3N(C2=O)CC(=O)O.Cl

Benazepril Hydrochloride(CAT: A000228) is a potent angiotensin-converting enzyme (ACE) inhibitor widely used in the management of hypertension, congestive heart failure, and kidney protection, especially in diabetic patients. It acts by blocking the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, thereby promoting vasodilation and lowering blood pressure. As a prodrug, it is converted in the liver to its active form, benazeprilat. Benazepril hydrochloride is typically supplied as a white to off-white crystalline powder and is sparingly soluble in water. It is also used in veterinary medicine, particularly in dogs and cats, for treating chronic heart and kidney conditions.