Becotatug

• CAT Number: I040382
• CAS Number: 2648260-93-7
• Purity: ≥95%

Becotatug(CAT: I040382) is a humanized IgG4 monoclonal antibody designed to selectively inhibit IL‑17A, a pro-inflammatory cytokine implicated in multiple immune-mediated diseases. By neutralizing IL‑17A, Becotatug effectively reduces downstream signaling that drives tissue inflammation and autoimmunity. It has demonstrated potent efficacy in preclinical models of psoriasis, psoriatic arthritis, and ankylosing spondylitis, showing rapid symptom relief and improved histopathology. Its optimized Fc region enhances stability while minimizing effector functions, supporting a favorable safety profile. Supplied at high purity, Becotatug is ideal for in vitro and in vivo research focused on cytokine-targeted immunotherapies, inflammation biology, and autoimmune disease mechanisms.